Long ago I had a boyfriend who did a whole paper about user interfaces (GUI) for a college class. It was really well done - explaining things like how in German cars the reverse gear is next to the 1st gear. Which makes more sense than how the Japanese and American cars do it. Since then I kind of look for these things.
Today I put Dreamweaver on my Mac at work to kind of learn it in the different way that Mac would be versus Windows. The first thing I noticed is that the files and folder are listed alphabetically. In Windows land, the folders are listed alpha and then the files in alpha. On Mac, they are all together and in alpha. Which makes more sense when you are doing a web site. In fact it starts to make more sense all together. It's logical to list everything. My brain of course naturally thinks folder or file, then look for it in alphabetical order. People don't normally think that way. Kind of fun learning these significant differences.
Next I have to learn to control the windows more like a Mac user. In Windows I minimize everything as I go along. Things are alien to me still on the Mac side.